Publications

IntakeYearFirstNameLastNamePublication
2009GregoryRossRoss GA, Morris GM, Biggin PC (2012) Rapid and Accurate Prediction and Scoring of Water Molecules in Protein Binding Sites. PLoS ONE 7(3): e32036
2009LeilaAlexanderLori C, Lantella A, Pasquo A, Alexander LT, Knapp S, Chiaraluce R, & Consalvi V (2013) Effect of single amino acid substitution observed in cancer on Pim-1 kinase thermodynamic stability and structure. PLOS ONE (in press, accepted)
2010JamesDunbarJ. Dunbar, A. Fuchs, J. Shi, CM. Deane, ABangle: Characterising the VH-VL orientation in antibodies, Protein Eng. Des. & Sel., 2013, 26(10), 611-620
2011DavidBowkettPresented a poster (Phylogenetic Analysis of Plant Homeodomain Fingers) at 3rd Oxford Symposium on Epigenetics Mechanisms in Health and Disease.
2011DavidBowkettWon SABS-IDC short project prize 2012
2011RadoslawNowak"Chemical tools for human 2-oxoglutarate dependent oxygenases NO66 and MINA53", Radoslaw Nowak, Catrine Johansson, Anthony Tumber, Dafydd Owen, David Pryde, Udo Oppermann, 3rd Oxford Symposium on Epigenetics Mechanisms in Health and Disease: Neuropsychiatry and inflamation: epigenetic target discovery beyond oncology. Oxford, March 14-15, 2013, SBS.
2010Anthony JamesConnorAnthony Connor, Jonathan Cooper, Helen Byrne, Philip Maini, Steve McKeever, 'Object-Oriented Paradigms for Modelling Vascular Tumour Growth: a Case Study'. Proceedings of SIMUL 2012, The Fourth International Conference on Advances in System Simulation, 18
2010Anthony JamesConnorMcKeever, S., Gill, M., Connor, A. J., & Johnson, D. (2013). Abstraction in Physiological Modelling Languages (pp. 1–8). Accepted (to be presented at the 3rd International Workshop on Model-driven Approaches for Simulation Engineering).
2010Anthony JamesConnorDavid Johnson, Anthony Connor, Steve McKeever, 'Modular Markup for Simulating Vascular Tumour Growth'. Proceedings of the 5th International Advanced Research Workshop on In Silico Oncology and Cancer Investigation (5th IARWISOCI) - The TUMOR Workshop, 22-
2010AndrewElliottElliott, A: 'A systematic study of Parkinson’s disease network construction through sub-sampling and seed lists'. EMBL Networks in the Life Sciences Workshop (October 2012)
2010JeanHelieINTERACTIONS OF TWO AMPHIPATHIC CELL-PENETRATING PEPTIDES WITH COMPLEX MODEL MEMBRANES: INSIGHTS FROM MOLECULAR DYNAMICS SIMULATIONS
Author Block: Jean Helie1, Francesca Milletti2, Charlotte M. Deane1, Mark S.P. Sansom1.
1Oxford University, Oxford, United Kingdom, 2Hoffmann-La Roche, Nutley, NJ, USA, it was presented in 2013 at the 57th Biophysical Society Annual Meeting
2010JamesDunbarEMTRAIN workshop at AstraZeneca where I presented my research to other industrially sponsored PhD students from across Europe
2010Nicholas CharlesDunkleyPatient-specific Predictions in the Intensive Care Unit using a Bayesian Ensemble Alistair Johnson, Nic Dunkley, Louis Mayaud, Athanasios Tsanas, Andrew Kramer and Gari Clifford
2010Nicholas CharlesDunkleyComputing in Cardiology Challenge (2012).
2010LauraJenningsReview: Progress in the development and application of small molecule inhibitors of bromodomain-acetyl-lysine interactions. J. Med. Chem. 55:9393 (2012) Jennings, L and Rooney, T
2010Henry RobertWilman3Dsig, 13th July 2012, Long Beach California. Oral presentation: Kinks in Transmembrane Helices. Henry R. Wilman, Jiye Shi, Charlotte M. Deane.
2010Henry RobertWilmanPoster Prize at UCB PhD Day, October 2012
2009Kok PhinChooiNov 2011: Commendation for performance at PRS transfer viva (Department of Organic Chemistry, Oxford)
Nov 2011: Commendation for performance at PRS transfer viva (Department of Organic Chemistry, Oxford)
2009JieqingJiaoJiao, J., Salinas, C.A., Searle, G.E., Gunn, R.N., Schnabel, J.A.: Joint estimation of subject motion and tracer kinetic parameters of dynamic PET data in an EM framework. Proc. SPIE 83140A (2012).
2009JieqingJiaoJiao, J., Searle, G.E., Schnabel, J.A., G.E., Gunn, R.N.: Pharmacokinetic model based groupwise image registration of 4D brain PET data and its impact on clinical occupancy studies with [11C]-(+)-PHNO. International Symposium on Cerebral Blood Flow, Metab
2009JieqingJiaoJiao, J., Searle, G.E., Tziortzi, A.C., Salinas, C.A., Gunn, R.N., Schnabel, J.A.: Spatio-temporal pharmacokinetic model based registration of 4D brain PET data. Proc. MICCAI Workshop on Spatiotemporal Image Analysis for Longitudinal and Time-Series Image
2009JieqingJiaoJiao, J., Schnabel, J.A., Gunn, R.N.: A Generalised Spatio-Temporal Registration Framework for Dynamic PET Data: Application to Neuroreceptor Imaging. (under review
2009JieqingJiaoJiao, J., Searle, G.E., Tziortzi, A.C., Salinas, C.A., Gunn, R.N., Schnabel, J.A.: Spatio-temporal pharmacokinetic model based registration of 4D PET neuroimaging data. (under review)
2009JieqingJiao2011: CSSAUK High-Level Entrepreneurship Challenge Honourable Mention
2009JieqingJiao2013: ISCBFM Young Investigator Travel Bursary by International Symposium on Cerebral Blood Flow, Metabolism and Function and International Conference on Quantification of Brain Function with PET
2009JieqingJiao2012: Guarantors of Brain Student Award
2009MatthiasSchmidtSimulation-Based Prediction of Phosphatidylinositol 4,5-Bisphosphate Binding to an Ion Channel. Matthias R. Schmidt, Phillip J. Stansfeld, Stephen J. Tucker, Mark S.P. Sansom (Biochemistry, 2012).
2009MatthiasSchmidtFeatured in PSI Nature "Research Advances section" for March 2012
2009MatthiasSchmidtState-Independent Intracellular Access of Quaternary Ammonium Blockers to the Pore of TREK-1. Markus Rapedius (*), Matthias R. Schmidt (*), Chetan Sharma, Phillip J. Stansfeld, Markus Rapedius, Mark S.P. Sansom, Thomas Baukrowitz, Stephen J. Tucker (Chann
2009MatthiasSchmidtStructure of a KirBac Potassium Channel with an Open Bundle-Crossing Indicates a Mechanism of Channel Gating. Vassily N. Bavro, Rita de Zorzi, Matthias R. Schmidt, Joao R.C. Muniz, Lejla Zubcevic, Mark S.P. Sansom, Catherine Venien-Bryan, Stephen J. Tucke
2009MatthiasSchmidtStructure of a KirBac Potassium Chann el with an Open Bundle-Crossing Indicates a Mechanism of Channel Gating. Vassily N. Bavro (*), Rita de Zorzi (*), Matthias R. Schmidt, Joao R.C. Muniz, Lejla Zubcevic, Mark S.P. Sansom, Catherine Venien-Bryan, Stephen
2009MatthiasSchmidtState-Independent Intracellular Access of Quaternary Ammonium Blockers to the Pore of TREK-1. Markus Rapedius (*), Matthias R. Schmidt (*), Chetan Sharma, Phillip J. Stansfeld, Markus Rapedius, Mark S.P. Sansom, Thomas Baukrowitz, Stephen J. Tucker (Chann
2009MatthiasSchmidtR.deBoer, D.Klunder, R.Penterman, C.deWitz, R.Schroeders, J.Lub,M.R.Schmidt, Advances in Microarray Technologies,Stockholm,Sweden,2009 (Poster)
2009MatthiasSchmidtM.R.Schmidt, Philips Technical Note PR-­‐TN 2006/01132: Optical spectroscopy on joints for rheumatoid arthritis
2009MatthiasSchmidtM.R. Schmidt, Philips Technical Note PR-­‐TN 2009/00302: The wire grid biosensor for nucleic acid testing
2009KonradKrawczyki-Patch web service: inter-protein contact prediction using local network information, Krawczyk, K., Hamer R., Luo, Q., Armitage, J., Reinert, G., Deane, C.M.; poster presented at ECCB 2010.
2009LydiaLe PageBritish Chapter of ISMRM, Manchester, MT 2011/12, Oral presentation: Assessment of PDK inhibition in the isolated perfused rat heart using hyperpolarized pyruvate
2009LydiaLe PageAlternative Muscle Club, Oxford, TT 2011, Flash Talk: Development and Application of Magnetic Resonance techniques for studying drug effects in the healthy and diseased heart.
2009MatthiasSchmidtM.R.Schmidt, P.J.Stansfeld, M.Rapedius T.Baukrowitz, S.J.Tucker, M.S.P.Sansom, Biophysical Journal,vol.100,issue 3, pp 431a, Baltimore
2009LydiaLe PageThe International Society for Magnetic Resonance in Medicine, Melbourne, HT 2012, e-Poster: Investigating pharmacological modification of cardiac pyruvate metabolism using hyperpolarized magnetic resonance
2009LydiaLe PageImaging Festival, Oxford, MT 2012/13, Poster: Assessment of real-time cardiac and hepatic glucose metabolism in the diabetic rat
2009LydiaLe PageEMTRAIN workshop, Manchester, HT2012, Oral presentation: Development and Application of Magnetic Resonance Techniques for the Study of Drug Effects on Metabolism in the Healthy and Diseased Heart
2009LydiaLe PageSociety for Heart and Vascular Metabolism, Oxford, TT 2012, Poster: Real-time assessment of pharmacologically altered metabolism in the rat heart using hyperpolarised [1-13C] pyruvate
2009LydiaLe PageMitOx Meeting, Oxford, MT 2012/13, Oral Presentation: Assessment of real-time, in vivo cardiac and hepatic glucose metabolism in the diabetic rat using hyperpolarized 13C pyruvate, Won best PhD presentation, sponsored by Merck
2009LydiaLe PageDiabetes UK, Manchester, HT 2013, Poster: Assessment of real-time, in vivo cardiac and hepatic glucose metabolism in the diabetic rat, using hyperpolarized 13C pyruvate
2009TimothyRooneyREVIEW: Progress in the development and application of small molecule inhibitors of bromodomain-acetyl-lysine interactions. Hewings, D. S.; Rooney, T. P. C.; Jennings, L. E.; Hay, D.; Schofield, C. J.; Brennan, P. E.; Knapp, S.; Conway, S. J.,J. Med. Chem., 2012, 55, 9393.
2009TimothyRooneyMarch 2013: Bronze award for chemistry research presented at SET for BRITAIN, house of commons.
2009TimothyRooneyDecember 2011: Prize for poster presented at Biological and Medicinal Chemistry Symposium.
2009TimothyRooneyApril 2012: David Kelly prize for best poster at Bio-Organic Postgraduate Symposium.
2009MatthiasSchmidtStructural and Mechanistic Insights into Gating of K2P Channels. M. Rapedius, P.L. Piechotta, P.J. Stansfeld, M.R. Schmidt, M.K. Bollepalli, G. Ehrlich, I. Andres-Enguix, H. Fritzenschaft, N. Decher, M.S.P. Sansom, S.J. Tucker, T. Baukrowitz (Poster at the Biophysical Society Meeting, San Diego, March 2012).
2009MatthiasSchmidtX-Ray Crystal Structure of a Prokaryotic Kir channel in an Open Conformation: Insights into the Mechanism of Opening at the Bundle-Crossing Gate. Vassily N. Bavro (*), Rita de Zorzi (*), Matthias R. Schmidt, Joao R.C. Muniz, Lejla Zubcevic, Mark S.P. Sansom, Catherine Venien-Bryan, and Stephen J. Tucker. (Poster presented at the meeting of the Physiological Society in Oxford, July 2011)
2012JinwooLeemDunbar, J., Krawczyk, K., Leem J., Baker T., Fuchs A., Georges G., Shi J., and Deane C.M. (2014). Nucleic Acids Res. 42. D1140-D1146
2011StefanVerhoogMizuta, S.; Galicia-López, O.; Engle, K. M.; Verhoog, S.; Wheelhouse, K.; Rassias, G.; Gouverneur, V. Chemistry – A European Journal 2012, 18, 8583-8587.
2011StefanVerhoogGao, Z.; Lim, Y. H.; Tredwell, M.; Li, L.; Verhoog, S.; Hopkinson, M.; Kaluza, W.; Collier, T. L.; Passchier, J.; Huiban, M.; Gouverneur, V. Angew. Chem. Int. Ed. 2012, 51, 6733-6737.
2011SamuelGrayerCH-01 is a Hypoxia-Activated Prodrug That Sensitizes Cells to Hypoxia/Reoxygenation Through Inhibition of Chk1 and Aurora A Cindy Cazares-Körner, Isabel M. Pires, I. Diane Swallow, Samuel C. Grayer, Liam J. O’Connor, Monica M. Olcina, Martin Christlieb, Stuart J. Conway, and Ester M. Hammond Articles ASAP (As Soon As Publishable) Publication Date (Web): April 18, 2013 (Articles); ACS Chemical Biology
2011StefanVerhoogMizuta, S.; Engle, K. M.; Verhoog, S.; Galicia-López, O.; O’Duill, M.; Médebielle, M.; Wheelhouse, K.; Rassias, G.; Thompson, A. L.; Gouverneur, V. Organic Letters 2013, 15, 1250-1253.
2011StefanVerhoogMizuta, S.; Verhoog, S.; Engle, K. M.; Khotavivattana, T.; O’Duill, M.; Wheelhouse, K.; Rassias, G.; Médebielle, M.; Gouverneur, V. Journal of the American Chemical Society 2013, 135, 2505-2508.
2011RachelShamo SchillerSchiller, R.; Scozzafava, G.; Tumber, A.; Wickens, J. R.; Bush, J. T.; Rai, G.; Lejeune, C.; Choi, H.; Yeh, T.-L.; Chan, M. C.; Mott, B. T.; McCullagh, J. S. O.; Maloney, D. J.; Schofield, C. J.; Kawamura, A. A cell-permeable ester derivative of the JmjC histone demethylase inhibitor IOX1. ChemMedChem 2014, 9, 566–71.
2011AngelinaMeasuresJennings, L. E.; Measures, A. R.; Wilson, B. G.; Conway, S. J. Phenotypic Screening and Fragment-Based Approaches to the Discovery of Small-Molecule Bromodomain Ligands. Future Medicinal Chemistry 2014, 6, 179–204.
2010Kylie AnnBeattieK.A. Beattie, C. Luscombe, G. Williams, J. Munoz-Muriedas, D.J Gavaghan, Y. Cui, G.R. Mirams, Evaluation of an in silico cardiac safety assay: Using ion channel screening data to predict QT interval changes in the rabbit ventricular wedge, Journal of Pharmacological and Toxicological Methods (2013), http://dx.doi.org/10.1016/j.vascn.2013.04.004
2010JamesDunbarABangle: Characterising the VH-VL orientation in antibodies. J.Dunbar, A.Fuchs, J.Shi and C.M.Deane. Protein Engineering Design and Selection. 2013. doi:10.1093/protein/gzt020.
2010KylieBeattieBeattie, K. A., Luscombe, C., Williams, G., Munoz-Muriedas, J., Gavaghan, D. J., Cui, Y., & Mirams, G. R. (2013). Evaluation of an in silico cardiac safety assay: using ion channel screening data to predict QT interval changes in the rabbit ventricular wedge. Journal of pharmacological and toxicological methods, 68(1), 88-96
2010JamesDunbarJ. Dunbar, B. Knapp, A. Fuchs, J. Shi and CM. Deane. Examining variable domain orientations in antigen receptors gives insight into TCR-like antibody design, PLOS Comp. Bio., 2014, 10(9), e1003852
2010JamesDunbarB. Knapp, J. Dunbar and CM. Deane. Large Scale Characterization of the LC13 TCR and HLA-B8 Structural Landscape in Reaction to 172 Altered Peptide Ligands: A Molecular Dynamics Simulation Study, PLOS Comp. Bio., 2014, 10(8), e1003748
2010JamesDunbarJ. Dunbar, K. Krawczyk, J. Leem, T. Baker, A. Fuchs, G. Georges, J. Shi and CM. Deane, SAbDab: the Structural Antibody Database, Nucleic Acids Res., 2014, 42, D1140-D1146
2010HenryWilmanWilman, H. R., Shi, J. and Deane, C. M. (2014), Helix kinks are equally prevalent in soluble and membrane proteins. Proteins: Structure, Function, and Bioinformatics 82: 1960–1970. doi: 10.1002/prot.24550
2010HenryWilmanHenry R. Wilman, Jean-Paul Ebejer, Jiye Shi, Charlotte M. Deane, and Bernhard Knapp (2014), Crowdsourcing Yields a New Standard for Kinks in Protein Helices. Journal of Chemical Information and Modeling 54 (9): 2585-2593
2009LydiaLe PageM.S. Dodd, D.R. Ball, M.A. Schroeder, L. M. Le Page, H. J. Atherton, L.C. Heather, A-M. Seymour, H. Ashrafian, H. Watkins, K. Clarke and D.J. Tyler, “In vivo alterations in cardiac metabolism and function in the spontaneously hypertensive rat heart”, Cardiovascular Research, 2012